Vitamin D, 2000 IU, daily
Vitamin D reduced the incidence of autoimmune disease by 40%, in a new study.
Dr JoAnn Manson, professor of medicine at Harvard Medical School, in collaboration with rheumatologists, Dr Jill Hahn and Dr Karen Costabader, just posted a new finding regarding the actions of supplemental vitamin D3.
They followed 25,000 adults, aged over 50 years, who took vitamin D3, 2000 IU daily, along with omega-3, for over 5 years.
They looked at a composite of autoimmune disorders, as well as individual conditions such as rheumatoid arthritis, polymyalgia rheumatica and psoriasis.
Vitamin D significantly reduced the risk of autoimmune disorders by 22%.
The omega-3 reduced the risk by 10%, or less.
Compared with a reference group who received placebos, the reduction in autoimmune diseases was greater than 30% with vitamin D + omega-3.
Then accounting for latency, among those who were in the trial for at least 2 years, the reduction was closer to 40%.
I should remind you that
(A) rheumatoid arthritis has been reliably linked to bowel and/or kidney infections caused by a germ, called Proteus Mirabilis.
Probably, the vitamin D reduced rheumatoid arthritis by killing Proteus.
(B) Polymyalgia rheumatica has been linked to increased production of interleukin-6 (IL-6), which the large bowel uses to heal damage to its mucosa, in diverticulitis.
Again, vitamin D would have a beneficial effect by killing the germs in the infected diverticulum.
(C) Psoriasis tends to be worse in people with thyroid conditions, especially hypothyroidism.
Vitamin D has been proven to be helpful in hypothyroidism.
(1) URL for Dr. Manson’s article:
(2) “Rheumatoid arthritis is caused by a Proteus urinary tract infection”, by Alan Ebringer 1 Taha Rashid, APMIS, 2014 May;122(5):363-8, doi: 10.1111/apm.12154. Epub 2013 8 29.
PMID: 23992372, DOI: 10.1111/apm.12154
(3)”Interleukin-6 in serum of patients with polymyalgia rheumatica & giant cell arteritis”,
by B Dasgupta 1 , G S Panayi, Br J Rheumatol. 1990 Dec;29
PMID: 2124160. DOI: 10.1093/rheumatology/29.6.456
(4) “Association of Psoriasis With Thyroid Disorders: A Hospital-Based, Cross-Sectional Study”, by Deepak Yumnam,1Naveen Kumar Kansal,1 and Ravi Kant2,
Published online 2022 Mar 9. doi: 10.7759/cureus.22987 , PMCID: PMC8991584,
(5) “Oral Vitamin D Therapy in Patients with Psoriasis”, by Ana Maria Alexandra Stanescu,1Anca Angela Simionescu,2,* and Camelia Cristina Diaconu ,
in Nutrients. 2021 Jan; 13(1): 163. Published online 2021 Jan 6. doi: 10.3390/nu13010163, PMCID: PMC7825555, PMID: 33419149
(6) “The Effects of Vitamin D Supplementation on Thyroid Function in Hypothyroid Patients”: a randomized, double-blind, placebo-controlled trial,
by Afsaneh Talaei,Fariba Ghorbani, and Zatollah Asemi1, in Indian J Endocrinol Metab. 2018 Sep-Oct; 22(5): 584–588. doi: 10.4103/ijem.IJEM_603_17 PMCID: PMC6166548 PMID: 30294564