IMAGINE TWIN CHIMPANZEES:-A PARABLE ON HEALTHY AGING ONCE UPON A TIME THERE WERE TWO CHIMPANZEES.They were twins, but one was smart and the other, not so very. On their third birthday each… ...
ADRENAL FATIGUE AND INTRACELLULAR HYPOTHYROIDISM-“ADRENAL FATIGUE” Transient stress causes short-term increase of cortisol output by the adrenal glands.Cortisol inhibits D1 (type 1, 5-deiodinase enzyme) and promotes D3, reducing conversion of T4 into T3, increasing… ...
ALZHEIMER’S DISEASE PREVENTION-Don’t wait until you develop Alzheimer’s disease - prevent it! On June 7th, 2021, the American Food and Drug Administration (FDA) “conditionally” approved Aducanumab (Aduhelm), an amyloid beta-directed monoclonal antibody… ...
Alzheimer’s, new treatments-We continue to be bombarded with scientific articles, detailing new modifiers and new treatments for Alzheimer’s disease: most of these are ineffective, but some reports do contain a hint of… ...
Anticancer plant virus-This just came into my newsfeed: I can't guarantee or recommend it, and although it looks encouraging, it may be one of those "leads" that just fizzles out and is… ...
Antioxidants lower dementia risk (pseudo-news)-The note below is from a report by Sharon Reynolds, dated 2022-05-24, on the NIH website (I have paraphrased it, for brevity and clarity). In "Antioxidants and DementiaMore Than Meets… ...
Apple Cider Vinegar-And now, some good news, for a change: it's about APPLE CIDER VINEGAR! Yesterday, the “Guardian” sent me an article by Amy Fleming, reporting on on apple cider vinegar research… ...
Artificial Sweetener, Erythritol-Erythritol and Heart Disease Who uses the artificial sweetener, erythritol? Here is a minimally altered report by F. Perry Wilson, MD, MSCE, Feb. 28, 2023. This is not my usual blog, in… ...
Biography of a Doctor-Abstract This is an autobiographical report of my own medical history of chronic stress and intracellular hypothyroidism, offered at the invitation of "Cureus" publishers and in the interest of furthering… ...
Brown Fat and Obesity-Everyone knows about FAT: we all care about it and everyone worries about it. Fat is among the most popular topics in the urbanized world, perhaps slightly less of a… ...
Burnout-According to the World Health Organization (WHO), occupational burnout is a result of chronic work-related stress, with symptoms characterized by "feelings of energy depletion or exhaustion; increased mental distance from… ...
CANCER TREATMENT WITH FAECAL TRANSPLANT-December, 2022: This note is from my newsfeed: I have no comments to make, but it seems important. The cancer–microbiome connection Zion Levi’s melanoma went into remission thanks to a… ...
Cholesterol, Statins, Strokes & IH-Medscape Medical News, a medical information newsfeed, sends me daily suggestions for articles to read, and I save the URLs for interesting items. In the batch I received on September… ...
CHRONIC FATIGUE SYNDROME-CFS is a type of intracellular hypothyroidism. A thyroid profile (TSH, T4, FT3, rT3)is diagnostic. Slow-release triiodothyronine is curative. ...
COMPOUNDED MEDICATION BAN-BROODING SUNSET The US FDA says that Bioidenticals are a “Public Health Concern”. A ban on BHRT is likely. From an article in the "Green Medicine" Magazine by Jonathan V.… ...
CONCUSSION RISK, IN SOCCER-2021-05-08: Teenage girls face almost double the risk of concussion playing soccer, compared with teenage boys (risk ratio 1.88, 95% confidence interval 1.69 to 2.09, P<0.001)…. Reported by Gareth Iacobucci.… ...
Covid 19 and INTERFERON-Re: interferon Covid 19 and "Long Covid" continue to present a thorny problem for individuals, doctors, nurses, hospitals and the public health system. Much has been written about Covid and… ...
DESSICATED THYROID RECALL-WEBMD HEALTH NEWS Some Thyroid Drugs Recalled Over Reduced Potency By Nancy Melville  May 04, 2021 -- In its third voluntary recall in the past year, Acella Pharmaceuticals has… ...
DHEA-The letters “DHEA” are an acronym for DEHYDROEPIANDROSTERONE: this is the hormone which is produced in greatest quantity by the youthful human body. In smaller animals, the hormone is produced… ...
DHEA AND THE HEART: A CASE REPORT-Herbert, age 66 Two of my healthiest patients ( humans, not cats! Herman, age 65 Back in 2006 two of my previously healthy, unmedicated male patients, Herman, aged 65 and… ...
DHEA cures cancer: one case.- BACKGROUND DHEA was first discovered as a urine metabolite in 1934 by Adolf Buteiiandt and Hans Dannenbaum from Germany. It was reaffirmed as a urinary metabolite in 1943 and isolated… ...
DHEA prevents cancer.-TP53 and DHEA This note was inspired by a very well-written, easy-to-read, but very long and complicated dissertation on how DHEA prevents cancer, entitled "DETECTION OF A NOVEL, PRIMATE-SPECIFIC ‘KILL… ...
DILATED CARDIOMYOPATHY CAUSED BY HYPOTHYROIDISM-This is a case report, titled Hypothyroidism-induced reversible dilated cardiomyopathy, by P Rastogi, A Dua, S Attri, and H Sharma, J Postgrad Med. 2018 Jul-Sep; 64(3): 177–179. doi: 10.4103/jpgm.JPGM_154_17, PMCID: PMC6066629PMID:… ...
Finasteride Warning (France)-France just Issued a "red box warning", with a QR code to facilitate complaints, to be attached to Finasteride Products by April 2023. 5 Dec., 2022: I just got the… ...
FUNCTIONAL MEDICINE-As I understand it, "functional medicine" includes:1] EDUCATED PATIENTS: The high school curriculum includes hormonal, metabolic and microbiome health as a formal subject, so that all understand health maintainance.2] HEALTH… ...
Healthcare crisis-The Ontario healthcare crisis Of all current hot topics in Ontario (in truth, across Canada), the healthcare crisis is “number 1”.Among recent headlines, a few (paraphrased, for brevity) stand out:… ...
HEART FAILURE PREVALENCE-This just in: 2% OF ADULTS IN EUROPE, NORTH AMERICA AND ISRAEL HAVE HEART FAILURE. A review in “News-Medical.Net “, by Emily Henderson, B.Sc., in “Medical Home Life Sciences” news… ...
HYPOTHYROIDISM – THE DEBATE re T3 and T4 therapy-Thyroid expert Dr. Antonio C. Bianco, MD, PhD, speaking at the American Association of Clinical Endocrinology (AACE) annual meeting about T3 and T4 therapy, has just acknowledged that many patients… ...
I need help with a minor concern-This website is a free medical information source for my old patients and anyone who needs info about hormones. I don't want to put annoying, indiscriminate ads on the site,… ...
IH (INTRACELLULAR HYPOTHYROIDISM)-Intracellular T3 deficiency Intracellular T3 deficiency, referred to in this article as Intracellular Hypothyroidism (IH), has been given many names, but has not been recognized as a bona fide metabolic… ...
Israeli – Hamas war: a Comment-The Controversy The controversy regarding "Israel’s right, to defend itself”, vs. the Palestinians’ complaints of discrimination and “underprivileged status” is currently a conversational “hot potato”: each side in the debate… ...
Just when you thought that family doctors would never learn about prescribing T3:-Jacqueline Jonklaas, Professor in the endocrinology division at Georgetown University, has submitted a paper entitled "Evidence-Based Use of Levothyroxine/Liothyronine Combinations in TreatingHypothyroidism" Below are excerpts from a (2nd March, 2021)… ...
Long Covid and IH-An opinion re. pathogenesis, diagnosis and management Long Covid: In 2021, I wrote a post entitled “Long Covid: a report from China” [1], in response to “Euthyroid Sick Syndrome (ESS),… ...
LONG COVID AND METFORMIN-A new article, which has created a stir in “Covid sciences” circles, was noticed and reported on 3/7/23, when it was still at the “preprint” stage: many news feeds carried… ...
Long Covid Complications-Long Covid, Depression and Anxiety This just in: a report, from “Medscape Medical News”, on an article documenting the neuropsychiatric complications of Long Covid, especially the high rates of depression… ...
LONG COVID DERMATITIS AND THE PRIMROSE-Here is one more anecdotal story. In February of 2020, my wife went to London for a conference, returning on the 5th of March.On the return trip she had a mild sore… ...
Long Covid: a report from china-Euthyroid Sick Syndrome (Functional Hypothyroidism) in Patients With COVID-19 Runmei Zou,1,†Chenfang Wu,2,†Siye Zhang,2Guyi Wang,2Quan Zhang,3Bo Yu,2Ying Wu,2Haiyun Dong,2Guobao Wu,2Shangjie Wu,4 and Yanjun Zhong2,* https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575767/ Published online 2020 Oct 7. doi: 10.3389/fendo.2020.566439PMCID:… ...
Lyme Disease and Thyroid Hormone-Figure 1: Borrelia Burgdorferi, dark-field microscopy(Wikipedia) About Lyme disease: its relationship to Intracellular Hypothyroidism: origin, symptoms, diagnosis, treatment. An old friend, who is an avid and successful vegetable gardener, is… ...
MACULAR DEGENERATION-On March 2nd, 2023, I got the current issue of the Green Medicine Newsletter, a monthly health blog, by Dr. Jonathan Wright, who is one of my Gurus.The subject this… ...
More about DCM-This new (August, 2021), very well-written paper, entitled "Thyroid Hormones—An Underestimated Player in Dilated Cardiomyopathy?",comes very close the truth of T3's influence on heart health and function.The authors have managed… ...
MORE, ON BAT (BROWN FAT)-Here we go, to BAT, again! Graphic 1, from Wikipedia: BAT cells have many active mitochondria and WAT cells have hardly any. On the other hand, white fat cells swell,… ...
Multiple Sclerosis and PEA-PEA (Palmitoylethanolamide) Today, I came across Dr. Alan Jacobs’ blog, of 2 March, 2022, regarding PEA (Palmitoylethanolamide), which helps to generate Allopregnanolone and is therefore helpful in the treatment of… ...
No more “Doctor” Harrys (at least, not in my family)-My great-grandfather, Philip Nathan "Archippus" Harry, MD, may his soul rest in peace, must be dismayed that the family tradition which he started is no more: two of his sons… ...
ON THE SUBJECT OF FIBROMYALGIA:-ON THE SUBJECT OF FIBROMYALGIA: The online literature is replete with both scientific and lay articles on fibromyalgia, the cause of which has not been elucidated and treatment for which… ...
POST-FINASTERIDE SYNDROME-PFS is due to 5-alpha reductase blockade, leading to Allopregnanolone deficiency and Functional Hypothyroidism. It should be treatable. ...
POSTPARTUM DEPRESSION MEDICATION COSTS $15,900, FOR 14 DAYS !-This just in (November 08, 2023), from Medscape news - A report, by Khushi Mandowara: a Biogen-Sage Therapeutics pill called Zurzuvae, is available for treating Postpartum Depression. Zurzuvae will cost $15,900, for… ...
Preventive care, as it could be-AbstractWithout preventive care, too many friends die because of late diagnosis, particularly of ovarian, colon, breast, lung, and pancreatic cancer.Instead of ongoing monitoring, with the emphasis on earliest possible diagnosis,… ...
Psychotherapy Tax-Your therapist must collect GST/HST One of my sons, who has qualified as a registered psychotherapist after 5 years of study, just told me about something which I find most… ...
RECENT ATTACKS ON MELATONIN SUPPLEMENTS-MELATONIN SUPPLEMENTS SUBJECTED TO LIBEL Over the past month or so, I have seen no less than 6 headlines in my news feed, to do with the dangers of taking… ...
Request for donations-Hi All, I just found an Article in JAMA (the Journal of the American Medical Association), dated June 21, 2021, by WK Silverstein and D. Grady, entitled "Overuse of Levothyroxine… ...
Rheumatoid Arthritis and HRT-Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research, by University of South Australia, in "Rheumatology" (2022). DOI: 10.1093/rheumatology/keac357 This paper appeared in… ...
rT3, according to the Mayo clinic:-"Generally, reverse triiodothyronine tests are not necessary since triiodothyronine should not be ordered in hospitalized or sick patients." ...
Schizophrenia risk in Afro-Caribbean Children, in UK-I just received a note in my “Guardian” newsfeed, regarding a much-lauded, best-selling book, entitled “Uprooting: From The Caribbean To The Countryside – Finding Home In An English Country Garden”,… ...
SHOULD MS Pts REDUCE MEAT INTAKE?-Alterations of host-gut microbiome interactions in multiple sclerosisThis admirable article is inconclusive, but suggests that MS patients might benefit from reduced meat consumption.See "INTERESTING URLs, to scientific papers", # 10. ...
Stress Causes Hypothyroidism-Why, Vs. How! Stress causes hypothyroidism, but explaining how it happens is like explaining how to remove this tree – I'll tell how stress causes hypothyroidism in notes on intracellular… ...
SUBSTACK-MESSAGE, to friends of cbhrt.ca, November 25, 2023 Hi, and best wishes, to all, for the festive season and the new year! Following much deliberation, I have elected to migrate… ...
T3 Inactivated in Heart Failure-INTRACELLULAR (FUNCTIONAL) HYPOTHYROIDISM Cardiomyocyte-specific inactivation of thyroid hormone in pathologic ventricular hypertrophy, by Christine J. Pol,Alice Muller, and Warner S. Simonides, was published in Nov. 2008. It proves Deiodinase-3 activity… ...
T3/rT3 Ratio in hypothyroidism-T3, reverse T3 (rT3) and the T3/rT3 ratio: The normal ranges The normal range for the T3/rT3 ratio is "greater than 20". The optimal range is greater than 24. The… ...
THINK ABOUT NORMAL-"NORMAL" = pristine pure product of honorable nature, like banana, or lovely HIBISCUS ! Before we begin, remember that I am not a professorial-level expert on this subject. Therefore what… ...
THYROID TESTS-SHOULD OUR THYROID HORMONAL ASSESSMENT BE REVIEWED? Currently, our “system” says that to figure out whether a person’s thyroid balance is satisfactory in terms of keeping our cells working at… ...
TREES reduce mortality-This report shines a light on an important fact: "money may not grow from trees, but something even better does". In a new study led by the US Department of… ...
Vitamin D Lowers Melanoma Risk-This just in: Ilkka T. Harvima, MD, PhD, et al., from the Department of Dermatology, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland, has filed a preliminary, but… ...
WHAT IS A HORMONE, AND WHY DO WE NEED THEM?-An endocrine hormone is a molecule produced by a hormone-secreting gland and carried by the blood to another organ, whose behavior it controls. Generally, the Hormone plugs into a specific… ...
WHY DO FOLKS DIE, WHILE RECOVERING FROM A HEART ATTACK?-New PAPER: re. MORTALITY AFTER HEART ATTACK I just received a recent paper, entitled "Association of Financial Strain With Mortality Among Older US Adults Recovering From an Acute Myocardial Infarction",… ...
XCRATH !-A SCIENCE-FICTION NOVEL BASED ON XENON, AS AN ANAESTHETIC AGENT A few folks have had a look at my book, entitled "XCRATH !" ! Isn't that nice ? It's a… ...
XCRATH!-Well, hello again! Those few of you who have chosen to follow this blog will, quite likely, have thought of this eventuality….. And here it is! I have just finished… ...
XENON, THE ATMOSPHERIC ANAESTHETIC-Xenon Xenon is the ideal anesthetic. Xenon is a trace gas in Earth's atmosphere, occurring at approximately 1 part per 11.5 million. It has 54 protons in its nucleus, so… ...