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    Lyme Disease and Thyroid Hormone

    About Lyme disease: its relationship to Intracellular Hypothyroidism: origin, symptoms, diagnosis, treatment. An old friend, who is an avid and successful vegetable gardener, is passionate about mushrooms, especially chanterelles (Fig. 2), which abound in the woods of Ontario and are easily found, if you know what to look for. So successful is he in the chanterelle hunt, that he is able to augment his income (a bit!) by selling them to knowledgeable restaurants. 2023 has been a bumper year, for chanterelles and my friend, while keeping himself amply supplied, sold his surplus for more than $1,000. In July however he…

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    Brown Fat and Obesity

    Everyone knows about FAT: we all care about it and everyone worries about it. Fat is among the most popular topics in the urbanized world, perhaps slightly less of a concern to the rural population and in some societies, an asset to some few. Our conversations about FAT are limited, most of the time, to “White” Adipose Tissue, referred to in the medical literature as WAT; most of us know nothing about brown fat – our Brown Adipose Tissue, jocularly nicknamed BAT. [1] Graphic from “ice bath science”, by Thomas P. Seager, PhD; https://www.morozkoforge.com/post/ice-bath-science [1] We have 2 types of…

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    Schizophrenia risk in Afro-Caribbean Children, in UK

    I just received a note in my “Guardian” newsfeed, regarding a much-lauded, best-selling book, entitled “Uprooting: From The Caribbean To The Countryside – Finding Home In An English Country Garden”, by Dr. Marchelle Farrell. [1]According to the Guardian newspaper, Dr. Farrell, a psychiatrist of African/Trinidadian origin who studied, and is working, in the UK, describes the dismay and anxiety which she experienced, on hearing that as an Afro-Caribbean migrant, any children she might have were highly likely to develop schizophrenia.She was advised that the risk of schizophrenia in the offspring of African/Caribbean-origin women, migrant to the UK, is “9 times…

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    Multiple Sclerosis and PEA

    PEA (Palmitoylethanolamide) Today, I came across Dr. Alan Jacobs’ blog, of 2 March, 2022, regarding PEA (Palmitoylethanolamide), which helps to generate Allopregnanolone and is therefore helpful in the treatment of the post-finasteride syndrome (PFS). [1] Palmitoylethanolamide (PEA) is a lipid (fat), found naturally in foods such as egg yolks and peanuts, and in the human body. PEA has analgesic, anti-inflammatory and analgesic effects in chronic neuropathic pain and arthritic pain and taking it reduces anxiety, promotes sleep and has other properties reminiscent of cannabinoids, although it is not a cannabinoid and does not attach to cannabinoid receptors. I was not…

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    Apple Cider Vinegar

    And now, some good news, for a change: it’s about APPLE CIDER VINEGAR! Yesterday, the “Guardian” sent me an article by Amy Fleming, reporting on on apple cider vinegar research by Dr. Darshna Yagnik (PhD). Ms. Fleming’s report is very well written and is easy to read and understand: Dr. Yagnik’s experience with taking ACV, and experimenting with it, is very nicely explained and the many beneficial effects of apple cider vinegar are clearly described. The article reminded me of a friend of mine A very good friend of mine had a problem: gastro-esophageal reflux (“acid reflux”), commonly known as…

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    Application of the T3/rT3 Ratio, in managing IH

    T3, reverse T3 (rT3) and the T3/rT3 ratio: The normal ranges The normal range for T3/rT3 is “greater than 20”: the optimal range is greater than 24. The normal T3 range is 3.1–6.1 (? 5.8) Pm/L (the T3 range was originally quoted as 3.1–6.1 pmol per litre: this was changed to 2.8–5.8 pmol per litre in 2021, but in my opinion the change was unfounded). I regard the correct range of T3 as 301-6.1. There is no “normal”range for rT3: reverse T3 is not regarded as a metabolite, because it is thought to have no function (although it does up-regulate…

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    Burnout

    According to the World Health Organization (WHO), occupational burnout is a result of chronic work-related stress, with symptoms characterized by “feelings of energy depletion or exhaustion; increased mental distance from one’s job, or feelings of negativism or cynicism related to one’s job; and reduced professional efficacy”.[1]While burnout may influence health, it is not itself classified by the WHO as a medical condition or mental disorder.[1] The WHO additionally states that “Burn-out refers specifically to phenomena in the occupational context and should not be applied to describe experiences in other areas of life”. However psychology today avers that burnout, though most…

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    Long Covid and IH

    An opinion re. pathogenesis, diagnosis and management Long Covid: In 2021, I wrote a post entitled “Long Covid: a report from China” [1], in response to “Euthyroid Sick Syndrome (ESS), in Patients with COVID-19”, by Runmei Zou, et al [2].Now, two years later, “long Covid” still affects approximately 10% of people who contract Covid 19, including a number of celebrities: so it is still a hot subject.I therefore feel it imperative that I comment on it once more. BackgroundSince long Covid was first described, much effort has been put into its investigation; but no firm answers have been forthcoming and…

  • Functional hypothyroidism - Hypothyroidism, - Iintracellular hypothyroidism

    IH (INTRACELLULAR HYPOTHYROIDISM)

    Intracellular T3 deficiency Intracellular T3 deficiency, referred to in this article as Intracellular Hypothyroidism (IH), has been given many names, but has not been recognized as a bona fide metabolic abnormality deserving of a formal title.Thus although the condition was definitively described in 2014, it has been ignored by mainstream medicine and its diagnostic panel has yet to be added to the medical armamentarium.It is time to accept this ubiquitous metabolic abnormality as the pervasive, important syndrome which it is.This article therefore is intended to educate the public, and not least, my colleagues, on the subject of intracellular thyroid 3…

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    Biography of a Doctor

    Abstract This is an autobiographical report of my own medical history of chronic stress and intracellular hypothyroidism, offered at the invitation of “Cureus” publishers and in the interest of furthering my colleagues’ knowledge of the syndrome from which I suffered for 40 years.My intent herein is to assist others in the prevention or alleviation of this condition.I offer this history without intent to compromise known and accepted methods of management and without a plan to profit in any way from its publication.I describe a 40 year history of steroidopenia and intracellular hypothyroidism (IH), which began at age 40. The step-by-step…