ALLOPREGNANOLONE

King of the Brain Hormones

Allopregnanolone, the Elephant Above the Clouds

ALLOPREGNANOLONE, produced from Progesterone by an enzyme called 5-alpha reductase and one called 3-alpha HSD, in both Neurons and Astrocytes, is the most important of the neurosteroids. Allopregnanolone production, facilitated by PEA (PalmitoylEthanolAmide), is the reason why PEA is recommended as a painkiller, as well as its sleep-promoting and mood elevating effects.

Wikipedia describes Allopregnanolone as (I quote) “stress reducing, rewarding, prosocial, anti-aggressive, pro-sexual, sedative, sleep facilitating, pro-cognitive, memory enhancing, analgesic, anticonvulsant, neuroprotective and neurogenic”.

I call Allopregnanolone“the brain’s housekeeper”, because it is the main actor in brain maintenance and repair.

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Published by Gervais

I am a Toronto-trained Urologist. I practiced in downtown Toronto, from 1977 to 1997, when I went to Saudi Arabia as chief of Urology at the Armed Forces (teaching) hospital in Tabuk. Returning to Toronto in Y2000, I switched to family practice. In 2007, began to prescribe Hormone Restoration Therapy and in 2012, I became a member of the American Academy of Antiaging Medicine [A4M]. I successfully wrote the A4M's written examination in December, 2013 and In May, 2016 I passed the oral examination, for accreditation as a BHRT consultant. In 2014 I began BHRT practice in Collingwood, Ontario and in January, 2017, joined the Stone Tree Naturopathic Clinic. Now I am 85 and retired, but it seems wasteful to jettison my learning and experience: the medical establishment knows nothing of BHRT / Functonal medicine and I feel obliged to offer my knowledge in the interest of those who are willing to think outside the box. QUALIFICATIONS: MB, BS, (UWI), 1964. LMCC 1969. FRCSC (Urology), 1974. ECFMG 1984. Florida license [inactive], ABAARM 2016. Affiliations: CSAMM, OMA, CMA, SUSO, CUA, RCP&S/C. PRACTICE TO DATE: Consultation in Functional Medicine: Chronic Fatigue Syndrome, Fibromyalgia, Andropause, Menopause, Teenage and Postpartum Depression/Panic Attacks, Thyroid Hormone malfunction, Infertility, Sexual Dysfunction and “the Undiagnosable”. ALL ARE WELCOME to read, comment or question!