Brain Fog is stress-related and temporary
Consider President Joe Biden’s lapse in these terms:
High-grade stress, including the “cruel and unusual” stress of a week of preparation for a momentous, 90 minute debate, must have caused considerable stress-related cortisol release: perhaps enough to produce Hypercortisolemia.
That being the case, Hypercortisolemia would have resulted in the blockade of Deiodinase 1, with resultant cessation of T3 production within his peripheral cells (D1 converts thyroid hormone, T4, to T3).
Hypercortisolemia would also have activated Deiodinase 3: D3 converts T4 into nonfunctional “reverse T3” and converts pre-existing T3, into T2, which is also nonfunctional. Thus all his cells would have been emptied of T3.
The net result would have been acute-onset Low T3 Syndrome, a hypothyroid state which I refer to as “Intracellular Hypothyroidism“(IH). In this condition, no T3 is made in the cells, so no T3 enters the bloodstream: hence, the “Low T3” moniker.
Intracellular hypothyroidism (“IH”, or Low T3 syndrome, if you prefer that term) presents clinically with severe fatigue, ennui, “fuzzy thinking” (which you might call “brain fog”) and confusion: a state in which an unbelievable apparition, such as Donald Trump, would cause a “Jesus Christ! What can I do about this?” reaction, rather than a “Bugger off! – you’re not real” reaction.
GOOD NEWS, MAYBE (!?!)
A blood test during the period of President Biden’s brain fog would have shown a serum T3 level of <4.0 (perhaps, less than 3.5) picomoles/litre and a reverse T3 of >13Ng/DL, which renders the IH diagnosis “most likely”. If the T3/rT3 ratio were less than 20, IH would have been confirmed – consult the T3/rT3 table, below.
Subscribe to continue reading
Subscribe to get access to the rest of this post and other subscriber-only content.