PFS is due to 5-alpha reductase blockade, leading to Allopregnanolone deficiency and Functional Hypothyroidism. It should be treatable.
The letters “DHEA” are an acronym for DEHYDROEPIANDROSTERONE: this is the hormone which is produced in greatest quantity by the youthful human body. In smaller animals, the hormone is produced entirely in the brain and blood levels tend to be very low. The brains of humans and the Primates also make DHEA, but in addition the adrenal glands process cholesterol into Pregnenolone, from which DHEA is made in such large amounts in youth, that weight-for-weight, it exceeds the aggregate of all the other hormones.DHEA levels are high at birth because the mother produces large amounts during pregnancy and the hormone…