Everyone knows about FAT: we all care about it and everyone worries about it. Fat is among the most popular topics in the urbanized world, perhaps slightly less of a concern to the rural population and in some societies, an asset to some few. Our conversations about FAT are limited, most of the time, to “White” Adipose Tissue, referred to in the medical literature as WAT; most of us know nothing about brown fat – our Brown Adipose Tissue, jocularly nicknamed BAT. [1] Graphic from “ice bath science”, by Thomas P. Seager, PhD; https://www.morozkoforge.com/post/ice-bath-science [1] We have 2 types of…
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I just received a note in my “Guardian” newsfeed, regarding a much-lauded, best-selling book, entitled “Uprooting: From The Caribbean To The Countryside – Finding Home In An English Country Garden”, by Dr. Marchelle Farrell. [1]According to the Guardian newspaper, Dr. Farrell, a psychiatrist of African/Trinidadian origin who studied, and is working, in the UK, describes the dismay and anxiety which she experienced, on hearing that as an Afro-Caribbean migrant, any children she might have were highly likely to develop schizophrenia.She was advised that the risk of schizophrenia in the offspring of African/Caribbean-origin women, migrant to the UK, is “9 times…
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PEA (Palmitoylethanolamide) Today, I came across Dr. Alan Jacobs’ blog, of 2 March, 2022, regarding PEA (Palmitoylethanolamide), which helps to generate Allopregnanolone and is therefore helpful in the treatment of the post-finasteride syndrome (PFS). [1] Palmitoylethanolamide (PEA) is a lipid (fat), found naturally in foods such as egg yolks and peanuts, and in the human body. PEA has analgesic, anti-inflammatory and analgesic effects in chronic neuropathic pain and arthritic pain and taking it reduces anxiety, promotes sleep and has other properties reminiscent of cannabinoids, although it is not a cannabinoid and does not attach to cannabinoid receptors. I was not…
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And now, some good news, for a change: it’s about APPLE CIDER VINEGAR! Yesterday, the “Guardian” sent me an article by Amy Fleming, reporting on on apple cider vinegar research by Dr. Darshna Yagnik (PhD). Ms. Fleming’s report is very well written and is easy to read and understand: Dr. Yagnik’s experience with taking ACV, and experimenting with it, is very nicely explained and the many beneficial effects of apple cider vinegar are clearly described. The article reminded me of a friend of mine A very good friend of mine had a problem: gastro-esophageal reflux (“acid reflux”), commonly known as…
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T3, reverse T3 (rT3) and the T3/rT3 ratio: The normal ranges The normal range for the T3/rT3 ratio is “greater than 20”. The optimal range is greater than 24. The normal FT3 range is 3.1–6.1 (? 5.8) Pm/L (the FT3 range was originally quoted as 3.1–6.1 pmol per litre: this was changed to 2.8–5.8 pmol per litre in 2021, but in my opinion the change was unfounded). I regard the correct range of FT3 as 3.1- 6.1. There is no “normal”range for rT3: The rT3 range, 5 – 25 ng/DL, as given in the medical literature, is nonsensical because (as…
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According to the World Health Organization (WHO), occupational burnout is a result of chronic work-related stress, with symptoms characterized by “feelings of energy depletion or exhaustion; increased mental distance from one’s job, or feelings of negativism or cynicism related to one’s job; and reduced professional efficacy”.[1] While burnout may influence health, it is not itself classified by the WHO as a medical condition or mental disorder.[1] The WHO additionally states that “Burn-out refers specifically to phenomena in the occupational context and should not be applied to describe experiences in other areas of life”. However “psychology today” avers that burnout, though…
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An opinion re. pathogenesis, diagnosis and management Long Covid: In 2021, I wrote a post entitled “Long Covid: a report from China” [1], in response to “Euthyroid Sick Syndrome (ESS), in Patients with COVID-19”, by Runmei Zou, et al [2].Now, two years later, “long Covid” still affects approximately 10% of people who contract Covid 19, including a number of celebrities: so it is still a hot subject and I feel it imperative that I comment on it once more.Note: here, the reference tags (#1 –10) are hyperlinked to the articles referenced. Background Since long Covid was first described, much effort…
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Intracellular T3 deficiency Intracellular T3 deficiency, referred to in this article as Intracellular Hypothyroidism (IH), has been given many names, but has not been recognized as a bona fide metabolic abnormality deserving of a formal title.Thus although the condition was definitively described in 2014, it has been ignored by mainstream medicine and its diagnostic panel has yet to be added to the medical armamentarium.It is time to accept this ubiquitous metabolic abnormality as the pervasive, important syndrome which it is.This article therefore is intended to educate the public, and not least, my colleagues, on the subject of intracellular thyroid 3…
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Abstract This is an autobiographical report of my own medical history of chronic stress and intracellular hypothyroidism, offered at the invitation of “Cureus” publishers and in the interest of furthering my colleagues’ knowledge of the syndrome from which I suffered for 40 years.My intent herein is to assist others in the prevention or alleviation of this condition.I offer this history without intent to compromise known and accepted methods of management and without a plan to profit in any way from its publication.I describe a 40 year history of steroidopenia and intracellular hypothyroidism (IH), which began at age 40. The step-by-step…
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This opinion piece is in response to an interesting report on fetal neurocognitive development, reviewed by Lily Ramsey, LLM, which I received today, Mar 29 2023.. It is entitled “Maternal weight gain in pregnancy and fetal neurodevelopmental disorders” The report, based on children born in Sweden from January 2007, to December 2010, was authored by Dr. Chinta Sidharthan, Rates of maternal weight gain over the course of pregnancy and offspring risk of neurodevelopmental disorders. Image Credit: Hazal Ak / Shutterstock Dr. Siddharthan, reporting on a Swedish study says (paraphrased): “Neurodevelopmental disorders (NDD) are prevalent. The main three, ASD, ADHD, and intellectual disability,…
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